Genome Instability in Development and Aging: Insights from Nucleotide Excision Repair in Humans, Mice, and Worms

DNA damage causally contributes to aging and cancer. Congenital defects in nucleotide excision repair (NER) lead to distinct cancer-prone and premature aging syndromes. The genetics of NER mutations have provided important insights into the distinct consequences of genome instability. Recent work in...

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Detalles Bibliográficos
Autores principales: Edifizi, Diletta, Schumacher, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598778/
https://www.ncbi.nlm.nih.gov/pubmed/26287260
http://dx.doi.org/10.3390/biom5031855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598778/
https://www.ncbi.nlm.nih.gov/pubmed/26287260
http://dx.doi.org/10.3390/biom5031855

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