Functional Role of NBS1 in Radiation Damage Response and Translesion DNA Synthesis

Nijmegen breakage syndrome (NBS) is a recessive genetic disorder characterized by increased sensitivity to ionizing radiation (IR) and a high frequency of malignancies. NBS1, a product of the mutated gene in NBS, contains several protein interaction domains in the N-terminus and C-terminus. The C-te...

Descripción completa

Detalles Bibliográficos
Autores principales: Saito, Yuichiro, Komatsu, Kenshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598784/
https://www.ncbi.nlm.nih.gov/pubmed/26308066
http://dx.doi.org/10.3390/biom5031990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598784/
https://www.ncbi.nlm.nih.gov/pubmed/26308066
http://dx.doi.org/10.3390/biom5031990

Ejemplares similares