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Functional Role of NBS1 in Radiation Damage Response and Translesion DNA Synthesis
Nijmegen breakage syndrome (NBS) is a recessive genetic disorder characterized by increased sensitivity to ionizing radiation (IR) and a high frequency of malignancies. NBS1, a product of the mutated gene in NBS, contains several protein interaction domains in the N-terminus and C-terminus. The C-te...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598784/ https://www.ncbi.nlm.nih.gov/pubmed/26308066 http://dx.doi.org/10.3390/biom5031990 |