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Managing Single-Stranded DNA during Replication Stress in Fission Yeast
Replication fork stalling generates a variety of responses, most of which cause an increase in single-stranded DNA. ssDNA is a primary signal of replication distress that activates cellular checkpoints. It is also a potential source of genome instability and a substrate for mutation and recombinatio...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598791/ https://www.ncbi.nlm.nih.gov/pubmed/26393661 http://dx.doi.org/10.3390/biom5032123 |