Paradoxical effect of rapamycin on inflammatory stress-induced insulin resistance in vitro and in vivo

Insulin resistance is closely related to inflammatory stress and the mammalian target of rapamycin/S6 kinase (mTOR/S6K) pathway. The present study investigated whether rapamycin, a specific inhibitor of mTOR, ameliorates inflammatory stress-induced insulin resistance in vitro and in vivo. We used tu...

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Detalles Bibliográficos
Autores principales: Yang, Ping, Zhao, Yunfei, Zhao, Lei, Yuan, Jun, Chen, Yao, Varghese, Zac, Moorhead, John F., Chen, Yaxi, Ruan, Xiong Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598825/
https://www.ncbi.nlm.nih.gov/pubmed/26449763
http://dx.doi.org/10.1038/srep14959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598825/
https://www.ncbi.nlm.nih.gov/pubmed/26449763
http://dx.doi.org/10.1038/srep14959

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