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ATP synthase subunit-β down-regulation aggravates diabetic nephropathy

In this study, we investigated the role of ATP synthase subunit-β (ATP5b) in diabetic nephropathy. Histopathological changes, fibrosis, and protein expressions of α-smooth muscle actin (α-SMA), advanced glycation end-products (AGEs), and ATP5b were obviously observed in the kidneys of db/db diabetic...

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Detalles Bibliográficos
Autores principales: Guan, Siao-Syun, Sheu, Meei-Ling, Wu, Cheng-Tien, Chiang, Chih-Kang, Liu, Shing-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598833/
https://www.ncbi.nlm.nih.gov/pubmed/26449648
http://dx.doi.org/10.1038/srep14561