EZH2-mediated loss of miR-622 determines CXCR4 activation in hepatocellular carcinoma

The CXC chemokine receptor 4 (CXCR4) exerts a variety of functions at different steps of hepatocellular carcinoma (HCC) progression. The molecular mechanisms and therapeutic value of CXCR4 in the development of HCC remain undefined. Here we show that aberrant CXCR4 overexpression is associated with...

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Detalles Bibliográficos
Autores principales: Liu, Haiou, Liu, Yidong, Liu, Weisi, Zhang, Weijuan, Xu, Jiejie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598861/
https://www.ncbi.nlm.nih.gov/pubmed/26404566
http://dx.doi.org/10.1038/ncomms9494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598861/
https://www.ncbi.nlm.nih.gov/pubmed/26404566
http://dx.doi.org/10.1038/ncomms9494

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