Cargando…

EZH2-mediated loss of miR-622 determines CXCR4 activation in hepatocellular carcinoma

The CXC chemokine receptor 4 (CXCR4) exerts a variety of functions at different steps of hepatocellular carcinoma (HCC) progression. The molecular mechanisms and therapeutic value of CXCR4 in the development of HCC remain undefined. Here we show that aberrant CXCR4 overexpression is associated with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Haiou, Liu, Yidong, Liu, Weisi, Zhang, Weijuan, Xu, Jiejie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598861/ https://www.ncbi.nlm.nih.gov/pubmed/26404566 http://dx.doi.org/10.1038/ncomms9494

Ejemplares similares

Author Correction: EZH2-mediated loss of miR-622 determines CXCR4 activation in hepatocellular carcinoma
por: Liu, Haiou, et al.
Publicado: (2021)

Bioinformatic Identification of miR-622 Key Target Genes and Experimental Validation of the miR-622-RNF8 Axis in Breast Cancer
por: Liu, Chuanyang, et al.
Publicado: (2019)

Hsa_circ_0101432 promotes the development of hepatocellular carcinoma (HCC) by adsorbing miR-1258 and miR-622
por: Zou, Haibo, et al.
Publicado: (2019)

Elevated expression of IFN-inducible CXCR3 ligands predicts poor prognosis in patients with non-metastatic clear-cell renal cell carcinoma
por: Liu, Weisi, et al.
Publicado: (2016)

High expression of interleukin-11 is an independent indicator of poor prognosis in clear-cell renal cell carcinoma
por: Pan, Deng, et al.
Publicado: (2015)

Tumor miR-125b predicts recurrence and survival of patients with clear-cell renal cell carcinoma after surgical resection
por: Fu, Qiang, et al.
Publicado: (2014)

Circ_0005918 Sponges miR-622 to Aggravate Intervertebral Disc Degeneration
por: Cui, Yan, et al.
Publicado: (2022)

miR-622 suppresses tumor formation by directly targeting VEGFA in papillary thyroid carcinoma
por: Wang, Renjie, et al.
Publicado: (2018)

Sevoflurane inhibits malignant progression of colorectal cancer via hsa_circ_0000231-mediated miR-622
por: Wang, Jingpeng, et al.
Publicado: (2021)

miR-622 Suppresses Tumor Formation by Directly Targeting VEGFA in Papillary Thyroid Carcinoma [Retraction]
Publicado: (2021)

miR-622 Counteracts the NUAK1-Induced Gastric Cancer Cell Proliferation and the Antioxidative Stress
por: Yang, Jian, et al.
Publicado: (2022)

Upregulation of miR-138 Increases Sensitivity to Cisplatin in Hepatocellular Carcinoma by Regulating EZH2
por: Zeng, Taohui, et al.
Publicado: (2021)

Decrease of miR-622 expression suppresses migration and invasion by targeting regulation of DYRK2 in colorectal cancer cells
por: Wang, Yong, et al.
Publicado: (2017)

Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways
por: Liu, Shuting, et al.
Publicado: (2021)

Klotho Endows Hepatoma Cells with Resistance to Anoikis via VEGFR2/PAK1 Activation in Hepatocellular Carcinoma
por: Chen, Lin, et al.
Publicado: (2013)

Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98
por: Alajez, N M, et al.
Publicado: (2010)

The suppressing role of miR-622 in renal cell carcinoma progression by down-regulation of CCL18/MAPK signal pathway
por: Li, Tian, et al.
Publicado: (2018)

EZH2 promotes hepatocellular carcinoma progression through modulating miR-22/galectin-9 axis
por: Chen, Shaofei, et al.
Publicado: (2018)

Identification of novel targets of miR-622 in hepatocellular carcinoma reveals common regulation of cooperating genes and outlines the oncogenic role of zinc finger CCHC-type containing 11
por: Gaza, Anne, et al.
Publicado: (2021)

The Tumorigenic Properties of EZH2 are Mediated by MiR-26a in Uveal Melanoma
por: Li, Yao, et al.
Publicado: (2021)

circEZH2(E2) (/E3 ) is a dual suppressor of miR363/miR708 to promote EZH2 expression and prostate cancer progression
por: Su, Zhengzheng, et al.
Publicado: (2022)

Retraction Note: The suppressing role of miR-622 in renal cell carcinoma progression by down-regulation of CCL18/MAPK signal pathway
por: Li, Tian, et al.
Publicado: (2023)

lncRNA SNHG6 regulates EZH2 expression by sponging miR-26a/b and miR-214 in colorectal cancer
por: Xu, Mu, et al.
Publicado: (2019)

MiR-32 Inhibits Proliferation and Metastasis by Targeting EZH2 in Glioma
por: Zhang, Yuan, et al.
Publicado: (2019)

Peritoneal Modulators of EZH2-miR-155 Cross-Talk in Endometriosis
por: Brunty, Sarah, et al.
Publicado: (2021)

Role of the EZH2/miR-200 axis in STAT3-mediated OSCC invasion
por: Wang, Yu, et al.
Publicado: (2018)

Role of the EZH2/miR-200 axis in STAT3-mediated OSCC invasion
por: Wang, Yu, et al.
Publicado: (2023)

MiR-340 Inhibits Triple-Negative Breast Cancer Progression by Reversing EZH2 Mediated miRNAs Dysregulated Expressions
por: Shi, Zhendong, et al.
Publicado: (2017)

miR-26a inhibits invasion and metastasis of nasopharyngeal cancer by targeting EZH2
por: YU, LI, et al.
Publicado: (2013)

EZH2-mediated Epigenetic Silencing of miR-29/miR-30 targets LOXL4 and contributes to Tumorigenesis, Metastasis, and Immune Microenvironment Remodeling in Breast Cancer
por: Yin, Huilong, et al.
Publicado: (2020)

miR-940 Suppresses Tumor Cell Invasion and Migration via Regulation of CXCR2 in Hepatocellular Carcinoma
por: Ding, Dong, et al.
Publicado: (2016)

miR-100 Suppresses the Proliferation, Invasion, and Migration of Hepatocellular Carcinoma Cells via Targeting CXCR7
por: Ge, Yiman, et al.
Publicado: (2021)

miR-92b promotes autophagy and suppresses viability and invasion in breast cancer by targeting EZH2
por: Liu, Fei, et al.
Publicado: (2018)

miR-17-5p and miR-19b-3p prevent osteoarthritis progression by targeting EZH2
por: Li, Yong, et al.
Publicado: (2020)

Circulating miR-340-5p and miR-506-3p as Two Osteo-miRNAs for Predicting Osteoporosis in a Cohort of Postmenopausal Women
por: Lu, Zifeng, et al.
Publicado: (2023)

miR-622 is a novel potential biomarker of breast carcinoma and impairs motility of breast cancer cells through targeting NUAK1 kinase
por: Orlandella, Francesca Maria, et al.
Publicado: (2020)

Plasma miR-15b-5p, miR-338-5p, and miR-764 as Biomarkers for Hepatocellular Carcinoma
por: Chen, Yi, et al.
Publicado: (2015)

Polycomb protein EZH2 suppresses apoptosis by silencing the proapoptotic miR-31
por: Zhang, Q, et al.
Publicado: (2014)

Targeting EZH1 and EZH2 contributes to the suppression of fibrosis-associated genes by miR-214-3p in cardiac myofibroblasts
por: Zhu, Wen-Si, et al.
Publicado: (2016)

P53 suppresses the progression of hepatocellular carcinoma via miR‐15a by decreasing OGT expression and EZH2 stabilization
por: You, Zhenyu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_26ok0t0j1rle81vuu1td926g69