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A novel combined RNA-protein interaction analysis distinguishes HIV-1 Gag protein binding sites from structural change in the viral RNA leader

RNA-protein interactions govern many viral and host cell processes. Conventional ‘footprinting’ to examine RNA-protein complex formation often cannot distinguish between sites of RNA-protein interaction and sites of RNA structural remodelling. We have developed a novel technique combining photo cros...

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Detalles Bibliográficos
Autores principales: Kenyon, Julia C., Prestwood, Liam J., Lever, Andrew M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598872/
https://www.ncbi.nlm.nih.gov/pubmed/26449409
http://dx.doi.org/10.1038/srep14369