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Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

Mesenchymal stem cells (MSCs) and macrophages are fundamental components of the stem cell niche and function coordinately to regulate haematopoietic stem cell self-renewal and mobilization. Recent studies indicate that mitophagy and healthy mitochondrial function are critical to the survival of stem...

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Detalles Bibliográficos
Autores principales: Phinney, Donald G., Di Giuseppe, Michelangelo, Njah, Joel, Sala, Ernest, Shiva, Sruti, St Croix, Claudette M., Stolz, Donna B., Watkins, Simon C., Di, Y. Peter, Leikauf, George D., Kolls, Jay, Riches, David W. H., Deiuliis, Giuseppe, Kaminski, Naftali, Boregowda, Siddaraju V., McKenna, David H., Ortiz, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598952/
https://www.ncbi.nlm.nih.gov/pubmed/26442449
http://dx.doi.org/10.1038/ncomms9472