Spotlight on decitabine for myelodysplastic syndromes in Chinese patients

Myelodysplastic syndromes (MDSs) are a group of heterogeneous clonal hematopoietic stem cell malignancies with advanced median age. The silencing of tumor suppressor genes caused by DNA hypermethylation plays a crucial role in the pathogenesis of MDS. Decitabine, the available hypomethylating agent,...

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Detalles Bibliográficos
Autores principales: Jing, Yu, Shen, Xue, Mei, Qian, Han, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599041/
https://www.ncbi.nlm.nih.gov/pubmed/26491353
http://dx.doi.org/10.2147/OTT.S81093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599041/
https://www.ncbi.nlm.nih.gov/pubmed/26491353
http://dx.doi.org/10.2147/OTT.S81093

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