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Circulating primers enhance platelet function and induce resistance to antiplatelet therapy

BACKGROUND: Aspirin and P2Y(12) antagonists are antiplatelet compounds that are used clinically in patients with thrombosis. However, some patients are ‘resistant’ to antiplatelet therapy, which increases their risk of developing acute coronary syndromes. These patients often present with an underly...

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Detalles Bibliográficos
Autores principales: Blair, T A, Moore, S F, Hers, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599128/
https://www.ncbi.nlm.nih.gov/pubmed/26039631
http://dx.doi.org/10.1111/jth.13022