Restoration of CCAAT enhancer binding protein α P42 induces myeloid differentiation and overcomes all-trans retinoic acid resistance in human acute promyelocytic leukemia NB4-R1 cells

All-trans retinoic acid (ATRA) is one of the first line agents in differentiation therapy for acute promyelocytic leukemia (APL). However, drug resistance is a major problem influencing the efficacy of ATRA. Identification of mechanisms of ATRA resistance are urgenly needed. In the present study, we...

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Detalles Bibliográficos
Autores principales: WANG, LIMENGMENG, XIAO, HAOWEN, ZHANG, XING, LIAO, WEICHAO, FU, SHAN, HUANG, HE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599186/
https://www.ncbi.nlm.nih.gov/pubmed/26397153
http://dx.doi.org/10.3892/ijo.2015.3163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599186/
https://www.ncbi.nlm.nih.gov/pubmed/26397153
http://dx.doi.org/10.3892/ijo.2015.3163

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