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An open-label, single-arm, phase I/II study of lower-dose decitabine based therapy in patients with advanced hepatocellular carcinoma

PURPOSE: We conducted this phase I/II clinical trial to determine the safety and efficacy of lower-dose decitabine based therapy in pretreated patients with advanced HCC. EXPERIMENTAL DESIGN: Patients with advanced HCC were eligible. The administered dose of decitabine was 6 mg/m(2)/d intravenously...

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Detalles Bibliográficos
Autores principales: Mei, Qian, Chen, Meixia, Lu, Xuechun, Li, Xiang, Duan, Feng, Wang, Maoqiang, Luo, Guangbin, Han, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599300/
https://www.ncbi.nlm.nih.gov/pubmed/25895027