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Instability in progressive multiple sequence alignment algorithms
BACKGROUND: Progressive alignment is the standard approach used to align large numbers of sequences. As with all heuristics, this involves a tradeoff between alignment accuracy and computation time. RESULTS: We examine this tradeoff and find that, because of a loss of information in the early steps...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599319/ https://www.ncbi.nlm.nih.gov/pubmed/26457114 http://dx.doi.org/10.1186/s13015-015-0057-1 |