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Impaired Development of Left Anterior Heart Field by Ectopic Retinoic Acid Causes Transposition of the Great Arteries

BACKGROUND: Transposition of the great arteries is one of the most commonly diagnosed conotruncal heart defects at birth, but its etiology is largely unknown. The anterior heart field (AHF) that resides in the anterior pharyngeal arches contributes to conotruncal development, during which heart prog...

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Detalles Bibliográficos
Autores principales: Narematsu, Mayu, Kamimura, Tatsuya, Yamagishi, Toshiyuki, Fukui, Mitsuru, Nakajima, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599416/
https://www.ncbi.nlm.nih.gov/pubmed/25929268
http://dx.doi.org/10.1161/JAHA.115.001889