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Dabigatran is Less Effective Than Warfarin at Attenuating Mechanical Heart Valve-Induced Thrombin Generation

BACKGROUND: Patients with mechanical heart valves (MHV) require warfarin to prevent thromboembolism. Although dabigatran was as effective as warfarin for stroke prevention in atrial fibrillation when compared with warfarin in patients with MHV, the study was stopped early because of more strokes and...

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Detalles Bibliográficos
Autores principales: Jaffer, Iqbal H, Stafford, Alan R, Fredenburgh, James C, Whitlock, Richard P, Chan, Noel C, Weitz, Jeffrey I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599481/
https://www.ncbi.nlm.nih.gov/pubmed/26304938
http://dx.doi.org/10.1161/JAHA.115.002322