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Dabigatran is Less Effective Than Warfarin at Attenuating Mechanical Heart Valve-Induced Thrombin Generation
BACKGROUND: Patients with mechanical heart valves (MHV) require warfarin to prevent thromboembolism. Although dabigatran was as effective as warfarin for stroke prevention in atrial fibrillation when compared with warfarin in patients with MHV, the study was stopped early because of more strokes and...
Autores principales: | Jaffer, Iqbal H, Stafford, Alan R, Fredenburgh, James C, Whitlock, Richard P, Chan, Noel C, Weitz, Jeffrey I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599481/ https://www.ncbi.nlm.nih.gov/pubmed/26304938 http://dx.doi.org/10.1161/JAHA.115.002322 |
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