Toward Personalized Medicine: Using Cardiomyocytes Differentiated From Urine-Derived Pluripotent Stem Cells to Recapitulate Electrophysiological Characteristics of Type 2 Long QT Syndrome

BACKGROUND: Human genetically inherited cardiac diseases have been studied mainly in heterologous systems or animal models, independent of patients’ genetic backgrounds. Because sources of human cardiomyocytes (CMs) are extremely limited, the use of urine samples to generate induced pluripotent stem...

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Detalles Bibliográficos
Autores principales: Jouni, Mariam, Si-Tayeb, Karim, Es-Salah-Lamoureux, Zeineb, Latypova, Xenia, Champon, Benoite, Caillaud, Amandine, Rungoat, Anais, Charpentier, Flavien, Loussouarn, Gildas, Baró, Isabelle, Zibara, Kazem, Lemarchand, Patricia, Gaborit, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599503/
https://www.ncbi.nlm.nih.gov/pubmed/26330336
http://dx.doi.org/10.1161/JAHA.115.002159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599503/
https://www.ncbi.nlm.nih.gov/pubmed/26330336
http://dx.doi.org/10.1161/JAHA.115.002159

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