Intracellular Na(+) Concentration ([Na(+)](i)) Is Elevated in Diabetic Hearts Due to Enhanced Na(+)–Glucose Cotransport

BACKGROUND: Intracellular Na(+) concentration ([Na(+)](i)) regulates Ca(2+) cycling, contractility, metabolism, and electrical stability of the heart. [Na(+)](i) is elevated in heart failure, leading to arrhythmias and oxidative stress. We hypothesized that myocyte [Na(+)](i) is also increased in ty...

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Detalles Bibliográficos
Autores principales: Lambert, Rebekah, Srodulski, Sarah, Peng, Xiaoli, Margulies, Kenneth B, Despa, Florin, Despa, Sanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599504/
https://www.ncbi.nlm.nih.gov/pubmed/26316524
http://dx.doi.org/10.1161/JAHA.115.002183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599504/
https://www.ncbi.nlm.nih.gov/pubmed/26316524
http://dx.doi.org/10.1161/JAHA.115.002183

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