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Increased urinary Smad3 is significantly correlated with glomerular hyperfiltration and a reduced glomerular filtration rate and is a new urinary biomarker for diabetic nephropathy

BACKGROUND: Diabetic nephropathy is one of the major microvascular complications of diabetes. We investigated the association between urinary Smad3 (usmad3) levels, glomerular hyperfiltration, and the development of nephropathy in patients with type 2 diabetes mellitus (T2DM). METHODS: The usmad3 le...

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Detalles Bibliográficos
Autores principales: Guo, Kaifeng, Lu, Junxi, Kou, Jingxin, Wu, Mian, Zhang, Lei, Yu, Haoyong, Zhang, Mingliang, Bao, Yuqian, Chen, Haibing, Jia, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599589/
https://www.ncbi.nlm.nih.gov/pubmed/26449625
http://dx.doi.org/10.1186/s12882-015-0156-8