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B-Cell and Monocyte Contribution to Systemic Lupus Erythematosus Identified by Cell-Type-Specific Differential Expression Analysis in RNA-Seq Data

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by complex interplay among immune cell types. SLE activity is experimentally assessed by several blood tests, including gene expression profiling of heterogeneous populations of cells in peripheral blood. To better understand...

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Detalles Bibliográficos
Autores principales: Dozmorov, Mikhail G., Dominguez, Nicolas, Bean, Krista, Macwana, Susan R., Roberts, Virginia, Glass, Edmund, James, Judith A., Guthridge, Joel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599594/
https://www.ncbi.nlm.nih.gov/pubmed/26512198
http://dx.doi.org/10.4137/BBI.S29470