Increased levels of interleukin-6 exacerbate the dystrophic phenotype in mdx mice

Duchenne muscular dystrophy (DMD) is characterized by progressive lethal muscle degeneration and chronic inflammatory response. The mdx mouse strain has served as the animal model for human DMD. However, while DMD patients undergo extensive necrosis, the affected muscles of adult mdx mice rapidly re...

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Detalles Bibliográficos
Autores principales: Pelosi, Laura, Berardinelli, Maria Grazia, Forcina, Laura, Spelta, Elisa, Rizzuto, Emanuele, Nicoletti, Carmine, Camilli, Carlotta, Testa, Erika, Catizone, Angela, De Benedetti, Fabrizio, Musarò, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599671/
https://www.ncbi.nlm.nih.gov/pubmed/26251044
http://dx.doi.org/10.1093/hmg/ddv323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599671/
https://www.ncbi.nlm.nih.gov/pubmed/26251044
http://dx.doi.org/10.1093/hmg/ddv323

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