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Intrinsic factors and the embryonic environment influence the formation of extragonadal teratomas during gestation

BACKGROUND: Pluripotent cells are present in early embryos until the levels of the pluripotency regulator Oct4 drop at the beginning of somitogenesis. Elevating Oct4 levels in explanted post-pluripotent cells in vitro restores their pluripotency. Cultured pluripotent cells can participate in normal...

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Detalles Bibliográficos
Autores principales: Economou, Constantinos, Tsakiridis, Anestis, Wymeersch, Filip J., Gordon-Keylock, Sabrina, Dewhurst, Robert E, Fisher, Dawn, Medvinsky, Alexander, Smith, Andrew JH, Wilson, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599726/
https://www.ncbi.nlm.nih.gov/pubmed/26453549
http://dx.doi.org/10.1186/s12861-015-0084-7