Ideal sphere-forming culture conditions to maintain pluripotency in a hepatocellular carcinoma cell lines

BACKGROUND: Cancer stem cells (CSCs) constitute 1–2 % of cancer tissue and are a major cause of tumor metastasis and recurrence. The culture environment is important in maintaining CSCs in vitro. Sphere formation is one method of culturing CSCs. In this study, we identified and validated optimal cul...

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Detalles Bibliográficos
Autores principales: Min, Seon Ok, Lee, Sang Woo, Bak, Seon Young, Kim, Kyung Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599746/
https://www.ncbi.nlm.nih.gov/pubmed/26457068
http://dx.doi.org/10.1186/s12935-015-0240-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599746/
https://www.ncbi.nlm.nih.gov/pubmed/26457068
http://dx.doi.org/10.1186/s12935-015-0240-y

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