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The impact of PPARα activation on whole genome gene expression in human precision cut liver slices

BACKGROUND: Studies in mice have shown that PPARα is an important regulator of lipid metabolism in liver and key transcription factor involved in the adaptive response to fasting. However, much less is known about the role of PPARα in human liver. METHODS: Here we set out to study the function of PP...

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Detalles Bibliográficos
Autores principales: Janssen, Aafke W.F., Betzel, Bark, Stoopen, Geert, Berends, Frits J., Janssen, Ignace M., Peijnenburg, Ad A., Kersten, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599789/
https://www.ncbi.nlm.nih.gov/pubmed/26449539
http://dx.doi.org/10.1186/s12864-015-1969-3