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The impact of PPARα activation on whole genome gene expression in human precision cut liver slices
BACKGROUND: Studies in mice have shown that PPARα is an important regulator of lipid metabolism in liver and key transcription factor involved in the adaptive response to fasting. However, much less is known about the role of PPARα in human liver. METHODS: Here we set out to study the function of PP...
Autores principales: | Janssen, Aafke W.F., Betzel, Bark, Stoopen, Geert, Berends, Frits J., Janssen, Ignace M., Peijnenburg, Ad A., Kersten, Sander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599789/ https://www.ncbi.nlm.nih.gov/pubmed/26449539 http://dx.doi.org/10.1186/s12864-015-1969-3 |
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