Cargando…

HuR and Ago2 Bind the Internal Ribosome Entry Site of Enterovirus 71 and Promote Virus Translation and Replication

EV71 (enterovirus 71) RNA contains an internal ribosomal entry site (IRES) that directs cap-independent initiation of translation. IRES-dependent translation requires the host’s translation initiation factors and IRES-associated trans-acting factors (ITAFs). We reported recently that mRNA decay fact...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Jing-Yi, Brewer, Gary, Li, Mei-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599798/
https://www.ncbi.nlm.nih.gov/pubmed/26451954
http://dx.doi.org/10.1371/journal.pone.0140291