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Regulation of Selenocysteine Content of Human Selenoprotein P by Dietary Selenium and Insertion of Cysteine in Place of Selenocysteine

Selenoproteins are a unique group of proteins that contain selenium in the form of selenocysteine (Sec) co-translationally inserted in response to a UGA codon with the help of cis- and trans-acting factors. Mammalian selenoproteins contain single Sec residues, with the exception of selenoprotein P (...

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Detalles Bibliográficos
Autores principales: Turanov, Anton A., Everley, Robert A., Hybsier, Sandra, Renko, Kostja, Schomburg, Lutz, Gygi, Steven P., Hatfield, Dolph L., Gladyshev, Vadim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599804/
https://www.ncbi.nlm.nih.gov/pubmed/26452064
http://dx.doi.org/10.1371/journal.pone.0140353