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Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross
New systems genetics approaches are needed to rapidly identify host genes and genetic networks that regulate complex disease outcomes. Using genetically diverse animals from incipient lines of the Collaborative Cross mouse panel, we demonstrate a greatly expanded range of phenotypes relative to clas...
Autores principales: | Gralinski, Lisa E., Ferris, Martin T., Aylor, David L., Whitmore, Alan C., Green, Richard, Frieman, Matthew B., Deming, Damon, Menachery, Vineet D., Miller, Darla R., Buus, Ryan J., Bell, Timothy A., Churchill, Gary A., Threadgill, David W., Katze, Michael G., McMillan, Leonard, Valdar, William, Heise, Mark T., Pardo-Manuel de Villena, Fernando, Baric, Ralph S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599853/ https://www.ncbi.nlm.nih.gov/pubmed/26452100 http://dx.doi.org/10.1371/journal.pgen.1005504 |
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