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Clostridium Perfringens Epsilon Toxin Binds to Membrane Lipids and Its Cytotoxic Action Depends on Sulfatide

Epsilon toxin (Etx) is one of the major lethal toxins produced by Clostridium perfringens types B and D, being the causal agent of fatal enterotoxemia in animals, mainly sheep and goats. Etx is synthesized as a non-active prototoxin form (proEtx) that becomes active upon proteolytic activation. Etx...

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Detalles Bibliográficos
Autores principales: Gil, Carles, Dorca-Arévalo, Jonatan, Blasi, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599917/
https://www.ncbi.nlm.nih.gov/pubmed/26452234
http://dx.doi.org/10.1371/journal.pone.0140321