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Beta Cell Mass Restoration in Alloxan-Diabetic Mice Treated with EGF and Gastrin

One week of treatment with EGF and gastrin (EGF/G) was shown to restore normoglycemia and to induce islet regeneration in mice treated with the diabetogenic agent alloxan. The mechanisms underlying this regeneration are not fully understood. We performed genetic lineage tracing experiments to evalua...

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Detalles Bibliográficos
Autores principales: Song, Imane, Patel, Oelfah, Himpe, Eddy, Muller, Christo J. F., Bouwens, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599944/
https://www.ncbi.nlm.nih.gov/pubmed/26452142
http://dx.doi.org/10.1371/journal.pone.0140148