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Beta Cell Mass Restoration in Alloxan-Diabetic Mice Treated with EGF and Gastrin
One week of treatment with EGF and gastrin (EGF/G) was shown to restore normoglycemia and to induce islet regeneration in mice treated with the diabetogenic agent alloxan. The mechanisms underlying this regeneration are not fully understood. We performed genetic lineage tracing experiments to evalua...
Autores principales: | Song, Imane, Patel, Oelfah, Himpe, Eddy, Muller, Christo J. F., Bouwens, Luc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599944/ https://www.ncbi.nlm.nih.gov/pubmed/26452142 http://dx.doi.org/10.1371/journal.pone.0140148 |
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