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Early Generation of New PrPSc on Blood Vessels after Brain Microinjection of Scrapie in Mice

Aggregation of misfolded host proteins in the central nervous system is believed to be important in the pathogenic process in several neurodegenerative diseases of humans, including prion diseases, Alzheimer’s disease, and Parkinson’s disease. In these diseases, protein misfolding and aggregation ap...

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Detalles Bibliográficos
Autores principales: Chesebro, Bruce, Striebel, James, Rangel, Alejandra, Phillips, Katie, Hughson, Andrew, Caughey, Byron, Race, Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600122/
https://www.ncbi.nlm.nih.gov/pubmed/26396245
http://dx.doi.org/10.1128/mBio.01419-15