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Early Generation of New PrPSc on Blood Vessels after Brain Microinjection of Scrapie in Mice
Aggregation of misfolded host proteins in the central nervous system is believed to be important in the pathogenic process in several neurodegenerative diseases of humans, including prion diseases, Alzheimer’s disease, and Parkinson’s disease. In these diseases, protein misfolding and aggregation ap...
Autores principales: | Chesebro, Bruce, Striebel, James, Rangel, Alejandra, Phillips, Katie, Hughson, Andrew, Caughey, Byron, Race, Brent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600122/ https://www.ncbi.nlm.nih.gov/pubmed/26396245 http://dx.doi.org/10.1128/mBio.01419-15 |
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