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Design and Characterization of a Sensorized Microfluidic Cell-Culture System with Electro-Thermal Micro-Pumps and Sensors for Cell Adhesion, Oxygen, and pH on a Glass Chip

We combined a multi-sensor glass-chip with a microfluidic channel grid for the characterization of cellular behavior. The grid was imprinted in poly-dimethyl-siloxane. Mouse-embryonal/fetal calvaria fibroblasts (MC3T3-E1) were used as a model system. Thin-film platinum (Pt) sensors for respiration (...

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Detalles Bibliográficos
Autores principales: Bonk, Sebastian M., Stubbe, Marco, Buehler, Sebastian M., Tautorat, Carsten, Baumann, Werner, Klinkenberg, Ernst-Dieter, Gimsa, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600170/
https://www.ncbi.nlm.nih.gov/pubmed/26263849
http://dx.doi.org/10.3390/bios5030513