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Design and Characterization of a Sensorized Microfluidic Cell-Culture System with Electro-Thermal Micro-Pumps and Sensors for Cell Adhesion, Oxygen, and pH on a Glass Chip
We combined a multi-sensor glass-chip with a microfluidic channel grid for the characterization of cellular behavior. The grid was imprinted in poly-dimethyl-siloxane. Mouse-embryonal/fetal calvaria fibroblasts (MC3T3-E1) were used as a model system. Thin-film platinum (Pt) sensors for respiration (...
Autores principales: | Bonk, Sebastian M., Stubbe, Marco, Buehler, Sebastian M., Tautorat, Carsten, Baumann, Werner, Klinkenberg, Ernst-Dieter, Gimsa, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600170/ https://www.ncbi.nlm.nih.gov/pubmed/26263849 http://dx.doi.org/10.3390/bios5030513 |
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