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Pyrazolopyrimidines: Potent Inhibitors Targeting the Capsid of Rhino- and Enteroviruses

There are currently no drugs available for the treatment of enterovirus (EV)-induced acute and chronic diseases such as the common cold, meningitis, encephalitis, pneumonia, and myocarditis with or without consecutive dilated cardiomyopathy. Here, we report the discovery and characterization of pyra...

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Detalles Bibliográficos
Autores principales: Makarov, Vadim A, Braun, Heike, Richter, Martina, Riabova, Olga B, Kirchmair, Johannes, Kazakova, Elena S, Seidel, Nora, Wutzler, Peter, Schmidtke, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600222/
https://www.ncbi.nlm.nih.gov/pubmed/26260222
http://dx.doi.org/10.1002/cmdc.201500304