Cargando…

Origin of Orthogonality of Strain-Promoted Click Reactions

Site-specific labeling of biomolecules is rapidly advancing due to the discovery of novel mutually orthogonal reactions. Quantum chemistry studies have also increased our understanding of their relative rates, although these have until now been based on highly simplified reactants. Here we examine a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wagner, Johannes A, Mercadante, Davide, Nikić, Ivana, Lemke, Edward A, Gräter, Frauke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600239/
https://www.ncbi.nlm.nih.gov/pubmed/26178299
http://dx.doi.org/10.1002/chem.201501727