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Long noncoding RNA lncTCF7, induced by IL-6/STAT3 transactivation, promotes hepatocellular carcinoma aggressiveness through epithelial-mesenchymal transition

BACKGROUND: Accumulating evidence suggests the pro-inflammatory cytokine interleukin-6 (IL-6) in tumor microenvironment may promote the development of hepatocellular carcinoma (HCC). However, the underlying mechanism remains largely unknown. METHODS: The expression and promoter activity of lncTCF7 w...

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Detalles Bibliográficos
Autores principales: Wu, Jun, Zhang, Jun, Shen, Bin, Yin, Kai, Xu, Jianwei, Gao, Wencan, Zhang, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600266/
https://www.ncbi.nlm.nih.gov/pubmed/26452542
http://dx.doi.org/10.1186/s13046-015-0229-3