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Long noncoding RNA lncTCF7, induced by IL-6/STAT3 transactivation, promotes hepatocellular carcinoma aggressiveness through epithelial-mesenchymal transition
BACKGROUND: Accumulating evidence suggests the pro-inflammatory cytokine interleukin-6 (IL-6) in tumor microenvironment may promote the development of hepatocellular carcinoma (HCC). However, the underlying mechanism remains largely unknown. METHODS: The expression and promoter activity of lncTCF7 w...
Autores principales: | Wu, Jun, Zhang, Jun, Shen, Bin, Yin, Kai, Xu, Jianwei, Gao, Wencan, Zhang, Lihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600266/ https://www.ncbi.nlm.nih.gov/pubmed/26452542 http://dx.doi.org/10.1186/s13046-015-0229-3 |
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