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Nortriptyline in knee osteoarthritis (NortIKA Study): study protocol for a randomised controlled trial

BACKGROUND: Osteoarthritis (OA) is a common cause of pain and disability. Currently available analgesics are often insufficiently effective or have unacceptable adverse effects. Tricyclic antidepressants may offer a useful centrally-acting analgesic. Nortriptyline is a readily-available, cheap and c...

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Detalles Bibliográficos
Autores principales: Hudson, Ben, Williman, Jonathan A., Stamp, Lisa K., Alchin, John S., Hooper, Gary J., Mangin, Dee, Thompson, Bronwyn F., Toop, Les
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600280/
https://www.ncbi.nlm.nih.gov/pubmed/26453560
http://dx.doi.org/10.1186/s13063-015-0961-1