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Nortriptyline in knee osteoarthritis (NortIKA Study): study protocol for a randomised controlled trial
BACKGROUND: Osteoarthritis (OA) is a common cause of pain and disability. Currently available analgesics are often insufficiently effective or have unacceptable adverse effects. Tricyclic antidepressants may offer a useful centrally-acting analgesic. Nortriptyline is a readily-available, cheap and c...
Autores principales: | Hudson, Ben, Williman, Jonathan A., Stamp, Lisa K., Alchin, John S., Hooper, Gary J., Mangin, Dee, Thompson, Bronwyn F., Toop, Les |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600280/ https://www.ncbi.nlm.nih.gov/pubmed/26453560 http://dx.doi.org/10.1186/s13063-015-0961-1 |
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