Increased susceptibility of CD4+ T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced CD4 and enhanced CXCR4 and FAS surface expression levels

BACKGROUND: Elderly HIV-1 infected individuals progress to AIDS more frequently and rapidly than people becoming infected at a young age. To identify possible reasons for these differences in clinical progression, we performed comprehensive phenotypic analyses of CD4+ T cells from uninfected young a...

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Detalles Bibliográficos
Autores principales: Heigele, Anke, Joas, Simone, Regensburger, Kerstin, Kirchhoff, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600300/
https://www.ncbi.nlm.nih.gov/pubmed/26452480
http://dx.doi.org/10.1186/s12977-015-0213-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600300/
https://www.ncbi.nlm.nih.gov/pubmed/26452480
http://dx.doi.org/10.1186/s12977-015-0213-1

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