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Deletion of glycerol channel aquaporin-9 (Aqp9) impairs long-term blood glucose control in C57BL/6 leptin receptor–deficient (db/db) obese mice

Deletion of the glycerol channel aquaporin-9 (Aqp9) reduces postprandial blood glucose levels in leptin receptor–deficient (db/db) obese mice on a C57BL/6 × C57BLKS mixed genetic background. Furthermore, shRNA-mediated reduction of Aqp9 expression reduces liver triacylglycerol (TAG) accumulation in...

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Detalles Bibliográficos
Autores principales: Spegel, Peter, Chawade, Aakash, Nielsen, Søren, Kjellbom, Per, Rützler, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600382/
https://www.ncbi.nlm.nih.gov/pubmed/26416971
http://dx.doi.org/10.14814/phy2.12538