SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef

HIV-1 Nef and the unrelated murine leukemia virus glycoGag strongly enhance the infectivity of HIV-1 virions produced in certain cell types in a clathrin-dependent manner. Here we show that Nef and glycoGag prevent the incorporation of the multipass transmembrane proteins SERINC3 and SERINC5 into HI...

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Detalles Bibliográficos
Autores principales: Usami, Yoshiko, Wu, Yuanfei, Göttlinger, Heinrich G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600458/
https://www.ncbi.nlm.nih.gov/pubmed/26416733
http://dx.doi.org/10.1038/nature15400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600458/
https://www.ncbi.nlm.nih.gov/pubmed/26416733
http://dx.doi.org/10.1038/nature15400

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