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PGC-1α controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity

Due to its role in regulation of mitochondrial function, PGC1α is emerging as an important player in ageing and neurodegenerative disorders. PGC1α exerts its neuroprotective effects by promoting mitochondrial biogenesis (MB) and functioning. However, the precise regulatory role of PGC1α in the contr...

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Detalles Bibliográficos
Autores principales: Dabrowska, Aleksandra, Venero, Jose Luis, Iwasawa, Ryota, Hankir, Mohammed-khair, Rahman, Sunniyat, Boobis, Alan, Hajji, Nabil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600622/
https://www.ncbi.nlm.nih.gov/pubmed/26363853