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Kinesin-5 is a microtubule polymerase

Kinesin-5 slides antiparallel microtubules during spindle assembly, and regulates the branching of growing axons. Besides the mechanical activities enabled by its tetrameric configuration, the specific motor properties of kinesin-5 that underlie its cellular function remain unclear. Here by engineer...

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Detalles Bibliográficos
Autores principales: Chen, Yalei, Hancock, William O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600729/
https://www.ncbi.nlm.nih.gov/pubmed/26437877
http://dx.doi.org/10.1038/ncomms9160