Eomesodermin-expressing T-helper cells are essential for chronic neuroinflammation

Development of acute experimental autoimmune encephalomyelitis (EAE) depends on Th17 cells expressing the nuclear factor NR4A2. However, in mice lacking NR4A2 in T cells, a late-onset disease is still inducible, despite a great reduction in acute inflammation. We here reveal that development of this...

Descripción completa

Detalles Bibliográficos
Autores principales: Raveney, Ben J. E., Oki, Shinji, Hohjoh, Hirohiko, Nakamura, Masakazu, Sato, Wakiro, Murata, Miho, Yamamura, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600741/
https://www.ncbi.nlm.nih.gov/pubmed/26436530
http://dx.doi.org/10.1038/ncomms9437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600741/
https://www.ncbi.nlm.nih.gov/pubmed/26436530
http://dx.doi.org/10.1038/ncomms9437

Ejemplares similares