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Eomesodermin-expressing T-helper cells are essential for chronic neuroinflammation

Development of acute experimental autoimmune encephalomyelitis (EAE) depends on Th17 cells expressing the nuclear factor NR4A2. However, in mice lacking NR4A2 in T cells, a late-onset disease is still inducible, despite a great reduction in acute inflammation. We here reveal that development of this...

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Detalles Bibliográficos
Autores principales:	Raveney, Ben J. E., Oki, Shinji, Hohjoh, Hirohiko, Nakamura, Masakazu, Sato, Wakiro, Murata, Miho, Yamamura, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600741/ https://www.ncbi.nlm.nih.gov/pubmed/26436530 http://dx.doi.org/10.1038/ncomms9437

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